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Adultsadminister 15 mg/kg by mouth once dailyDose adjustments are made based on patient’s blood countsPatient’s blood counts are monitored every two weeksIf the blood counts are in anacceptablerangethe dose may be increased by 5 mg/kg/day every 12 weeks until a maximum tolerated dosehighest dose that does not produce toxic blood countsor 35 mg/kg/day is reached.

Monitor blood counts at least once a week during HYDREA therapySevere anemia must be corrected before initiating therapy with HYDREAConsider dose modifications for other toxicities.

Taking didanosine or stavudine with hydroxyurea increases your risk of damage to your pancreas and liverYou also have increased risk of nerve pain.

Based on findings in animals and humansmale fertility may be compromised by treatment with HYDREAAzoospermia or oligospermiasometimes reversiblehas been observed in menInform male patients about the possibility of sperm conservation before the start of therapysee Chloromycetin online thesaurus ADVERSE REACTIONS and Nonclinical Toxicology

Pancreatitishepatotoxicityand peripheral neuropathy have occurred when hydroxyurea was administered concomitantly with antiretroviral drugsincluding didanosine and stavudinesee DRUG INTERACTIONS

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